Product information:
| Product name |
Ciprofloxacin Tablets |
| category |
Quinolones antibiotics. |
| Storage |
Cool and Dry Place |
| term of validity |
3 years |
Toxicology and pharmacology:
It belongs to fluoroquinolones with the same antibacterial spectrum as norfloxacin. Its antibacterial activity is the strongest among the widely used fluoroquinolones. In addition to the high antibacterial activity against gram-negative bacilli, it also has good antibacterial effect on Staphylococcus, and its effect on pneumococcus and Streptococcus is slightly less than that on Staphylococcus. It also has inhibitory effect on some mycobacteria, Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis. See norfloxacin for the mechanism of action and bacterial resistance. Quinolones are considered to act on the a subunit of DNA helicase in bacterial cells and inhibit DNA synthesis and replication, resulting in bacterial death.
Indication:
Ciprofloxacin is more widely used than norfloxacin in clinical use. In addition to urinary tract infection, intestinal infection and gonorrhea, ciprofloxacin can also be used for the treatment of influenza, Escherichia coli, pneumoniae, Proteus mirabilis, Proteus vulgaris, profeden, Morgan, Pseudomonas aeruginosa, Enterobacter cloacae, Citrobacter freundii, Staphylococcus (including methicillin-resistant strains) From the bone and joint infection, skin and soft tissue infection and pneumonia, sepsis and so on. It can be used for the treatment of severe infections, such as Enterobacteriaceae, pulmonary infection, abdominal cavity and biliary tract infection.
Adverse reactions:
The main symptoms were gastrointestinal reactions (3-4%), central nervous system symptoms (2%), allergic reactions (0.5-1.0%) and laboratory abnormalities (3-4%). Occasionally, epilepsy and even convulsions (excessive prone to occur). Most of the adverse reactions were mild, so it rarely affected the continuation of treatment. Crystal urine, joint pain or stiffness, light sensitivity, visual impairment and so on can occasionally occur in the course of treatment of norfloxacin. It can cause mild gastrointestinal irritation or discomfort, nausea, heartburn, loss of appetite, mild nervous system reaction, dizziness, drowsiness, headache, restlessness, and symptoms disappear after drug withdrawal (return to normal). Allergic reactions,
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