Product information:
| Product name |
Erythromycin Dry Suspension |
| Quality Standard |
Bp, USP |
| Storage |
Cool and Dry Place |
| Specifications |
125mg/5ml 60ml 250mg/5ml 60ml |
| Shelf Life |
36 Months |
What is erythromycin?
Erythromycin belongs to a group of drugs called macrolide antibiotics. Macrolide antibiotics slow the growth of, or sometimes kill, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.
Erythromycin is used to treat or prevent many different types of infections caused by bacteria.
Erythromycin may also be used for purposes not listed in this medication guide.
Side effects:
Get emergency medical help if you have signs of an allergic reaction to erythromycin (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
a seizure;
hearing problems (rare);
pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting; or liver problems - loss of appetite, stomach pain (upper right side), tiredness, easy bruising or bleeding, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Serious side effects may be more likely in older adults, including hearing loss, or a life-threatening fast heart rate.
Call your doctor if a baby using this medicine is vomiting or irritable with feeding.
Common erythromycin side effects may include:
severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
liver problems; or abnormal liver function tests.
pharmacological action:
Erythromycin is an alkaline antibiotic produced by Streptomyces erythreus, which belongs to macrolide. Erythromycin is a kind of bacteriostatic agent, but it also has bactericidal effect on highly sensitive bacteria at high concentration. Its mechanism of action is that it can reversibly bind to 50s subunits of bacterial ribosomes near donor site (P) through bacterial cell membrane, block the binding of tRNA to P site, and block the shift of polypeptide chain from receptor (a) to "P" position, so as to inhibit bacterial protein synthesis and thus play an antibacterial role. Erythromycin is only effective against active bacteria. Erythromycin has a broad antibacterial spectrum and is effective against most Gram-positive bacteria, some Gram-negative bacteria and some atypical pathogenic bacteria. Erythromycin has strong antibacterial activity against Staphylococcus (including enzyme producing strains), Streptococcus, pneumococcus, anthrax, Fusobacterium tetanus, diphtheria, Neisseria gonorrhoeae, meningococci, influenza bacilli, pertussis, Campylobacter jejuni, Legionella, Listeria, Israel actinomycetes, and has strong antibacterial activity against Treponema pallidum, Mycoplasma pneumoniae and hook Leptospira, Rickettsia, chlamydia and so on also had good inhibitory effect. Erythromycin lactobionate is the lactobionate of erythromycin. Erythromycin lactobionate was absorbed and hydrolyzed to release erythromycin. Erythromycin can bind to bacterial ribosomes reversibly near the donor site (P) through the bacterial cell membrane, blocking the transfer RNA (tRNA) binding to the "P" site, and blocking the displacement of the polypeptide chain from the receptor site (a) to the "P" site, so that the bacterial cell protein synthesis is inhibited, thus playing an antibacterial role. Erythromycin lactobionate is effective against most Gram-positive bacteria, some Gram-negative bacteria and some atypical pathogenic bacteria. Erythromycin has strong antibacterial activity against Staphylococcus (including enzyme producing strains), Streptococcus, pneumococcus, anthrax, Fusobacterium tetanus, diphtheria, Neisseria gonorrhoeae, meningococci, influenza bacilli, pertussis, Campylobacter jejuni, Legionella, Listeria, Israel actinomycetes, and has strong antibacterial activity against Treponema pallidum, Mycoplasma pneumoniae and hook Leptospira, Rickettsia and Chlamydia also had good inhibitory effect.
Indication:
1. Acute tonsillitis, acute pharyngitis and sinusitis caused by Streptococcus haemolyticus and Streptococcus pneumoniae.
2. Scarlet fever and cellulitis caused by hemolytic streptococcus.
3. Mycoplasma pneumoniae pneumonia and Chlamydia pneumoniae pneumonia.
4. Gas gangrene, anthrax and tetanus.
5. Diphtheria (adjuvant therapy) and diphtheria carrier.
6. Chlamydia trachomatis.
7. Urogenital infection caused by Chlamydia and mycoplasma.
8. Listeriosis.
9. Legionella pneumonia (Legionella disease).
10. Gonococcus infection.
11. Campylobacter jejuni enteritis.
12. Oral infection caused by anaerobic bacteria.
13. Whooping cough.
14. Actinomycosis.
15. Dermatology is mainly used for nongonococcal urethritis (Cervicitis), gonorrhea, syphilis, chancre, Chlamydia lymphogranuloma (venereal lymphogranuloma), acne, Staphylococcus aureus skin infection, scarlet fever, etc.
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