Product Information:
| Product name |
Piracetam Injection |
| Specification |
1g:5ml |
| Packing |
Customizable |
| Standard |
BP. USP. |
| Shelf life |
2 Years |
| Storage |
Cool and Dry Place |
Indication:
It is suitable for acute and chronic cerebrovascular diseases, brain trauma, various toxic encephalopathy and other causes of memory loss and mild and moderate brain dysfunction. It is also used in children with mental retardation.
Usage and dosage:
Intramuscular injection. 1 g each time, 2-3 times a day. Intravenous injection. 4-6g each time, twice a day. Intravenous drip. 4-8g each time, once a day, diluted to 250ml with 5% or 10% glucose injection or sodium chloride injection.
Adverse reactions:
1. The common gastrointestinal adverse reactions are nausea, abdominal discomfort, anorexia, abdominal distension, abdominal pain, etc. the severity of symptoms is directly related to the dosage of drugs.
2. The adverse reactions of central nervous system included excitement, irritability, dizziness, headache and insomnia, but the symptoms were mild and had nothing to do with the dosage. The above symptoms disappeared after withdrawal.
3. Mild liver function damage was occasionally seen, showing mild elevation of aminotransferase, but it had nothing to do with the drug dose.
Taboo:
1. It is forbidden for patients with extrapyramidal diseases, Huntington's disease and chorea.
2. It is forbidden for pregnant women.
3. Forbidden for newborns.
Medicine interactions:
The combination of this product and warfarin can prolong the prothrombin time and induce the inhibition of platelet aggregation. In patients receiving anticoagulation treatment, the coagulation time should be paid special attention to when using the product to prevent the risk of bleeding, and adjust the dosage and usage of anticoagulant treatment drugs.
Pharmacology:
This product is a drug for improving brain metabolism, belonging to the ring derivative of gamma aminobutyric acid. It can resist the brain function damage caused by physical and chemical factors. It can promote brain ATP, acetylcholine synthesis and nerve excitation conduction, and promote brain metabolism. It can resist the brain function damage caused by physical and chemical factors. It can improve the retrograde amnesia caused by hypoxia. Can enhance memory, improve learning ability.
Pharmacokinetics:
After entering the blood, the product reaches the brain and cerebrospinal fluid through the blood-brain barrier. The concentration in cerebral cortex and olfactory bulb is higher than that in brain stem. It is easy to pass through the placental barrier. The plasma protein binding rate was 30%, the half-life (T1 / 2) was 5-6 hours, and the volume of body distribution was 0.6 L / kg. Piracetam could not be decomposed by liver and excreted from urine and feces in its original form after oral administration. The elimination rate of kidney was 86 ml / min. The fecal output is about 1% - 2%.
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