Hydroxyethyl Starch 130/0.4 and sodium Chloride Injection
Name: Hydroxyethyl Starch 200/0.5 and Sodium Chloride Injection
Main ingredients: Hydroxyethyl Starch 200/0.5
Description This product is colorless or yellowish clear liquid.
Indication:
Treatment and prevention of circulatory insufficiency or shock (volume replacement therapy) associated with:
Surgery (hemorrhagic shock)
Trauma (traumatic shock)
Infection (septic shock)
Burn (burn shock)
Therapeutic hemodilution
Usage and dosage:
Intravenous drip.
The first 10-20ml should be input slowly, and the patient should be closely observed (because of the possibility of allergic reaction).
Daily dosage and infusion rate depend on blood loss, blood concentration and hemodilution effect.
The hematocrit of patients with normal heart and lung function should not be less than 30% when using colloidal dilator.
It is necessary to avoid cycle overload caused by too fast infusion and too large dosage.
1) Recommended dose for the treatment and prevention of circulatory insufficiency or shock (volume replacement therapy)
Unless otherwise required by the doctor.
Maximum daily dose:
20ml / kg per day according to body weight (about 1500ml per day according to 75kg body weight)
(about 2.0g hydroxyethyl starch / kg per day according to body weight)
The maximum infusion rate was 1
20ml / kg per hour according to body weight (about 1500ml per hour according to 75kg body weight)
(about 2.0g hydroxyethyl starch / kg per hour according to body weight)
2) Recommended dose for therapeutic hemodilution
The purpose of therapeutic hemodilution is to reduce hematocrit. It can be divided into normovolemic hemodilution (bleeding) and hypervolemic hemodilution (no bleeding). According to the dosage, it can be divided into low (250ml), medium (500ml) and high (2 × 500ml).
Daily dose: 250ml (low)
500ml (medium)
2 × 500ml (high)
Infusion rate: 250ml within 0.5-2 hours
500ml within 4-6 hours
2 × 500ml within 8-24 hours
Usage time:
1) Treatment and prevention of circulatory insufficiency or shock (volume replacement therapy)
There is no pharmacological and clinical evidence that this product can not be reused. The time and dose of treatment depend on the time and degree of hypovolemia.
2) Therapeutic hemodilution
For therapeutic hemodilution, 10 days of treatment is recommended.
Side effects:
Long term medium and high-dose infusion of this product, patients often have a kind of refractory itching, even after a few weeks of withdrawal, the symptoms may still occur, and may continue for several months, leading to emotional tension in patients.
In rare cases, renal pain may occur. Once the symptom occurs, the drug should be stopped immediately, and enough fluid should be added, and the serum creatinine value should be closely monitored.
When the dosage is higher, the bleeding time may be prolonged due to hemodilution, but it will not cause clinical bleeding. The decrease of hematocrit and dilution of plasma protein should be monitored.
contraindications:
-Severe congestive heart failure
-Renal failure (serum creatinine > 2 mg / dL or > 177 μ mol / L)
-Severe coagulopathy (but still considered for life-threatening emergencies)
-Liquid overload (excessive water) or severe liquid shortage (dehydration)
-cerebral hemorrhage
-Starch allergy
| Pruduct Name |
Specifications |
| Hydroxyethyl Starch 130/0.4 and Sodium Chloride Injection |
250ml:15g:2.25g / 500ml:30g:4.5g |
| Hydroxyethyl Starch 200/0.5 and Sodium Chloride Injection |
250ml:15g:2.25g / 500ml:30g:4.5g |
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