Product Information:
| Product name |
Cefmetazole Sodium for Injection |
| Specification |
0.25g, 0.5g , 1.0g, 2.0g |
| Package |
Customizable |
| Standard |
BP. USP |
| Storage |
Cool and Dry place |
| Shelf life |
2 Years |
Indication:
This product is suitable for the treatment of the following infections caused by Cefmetazole sodium sensitive Staphylococcus aureus, Escherichia coli, pneumonia, proteus, Morganella morganii, Providence, Bacteroides, peptococcus and provotella (except double route Prevotella)
Septicemia.
Acute bronchitis, pneumonia, secondary infection of chronic respiratory diseases, lung abscess and empyema.
Cholangitis and cholecystitis.
Peritonitis.
Pyelonephritis, cystitis.
Vestibular gland inflammation, intrauterine infection, uterine adnexitis, parauterine tissue inflammation.
Perimaxillofacial cellulitis and maxillitis.
Adverse reactions:
(1) It rarely causes shock (less than 0.01%), allergic reaction (discomfort, abnormal feeling of mouth, wheezing, dizziness, defecation, tinnitus, sweating, etc.) (the incidence is unknown). Therefore, attention should be paid to observation. If there is any abnormality, the drug should be stopped immediately and appropriate treatment should be taken.
(2) There may be Stevens Johnson syndrome (unknown incidence) and toxic epidermal necrosis (Lyell syndrome) (unknown incidence). Once similar symptoms are found, the drug should be stopped immediately and treated properly.
(3) Acute renal failure (unknown incidence) and other serious renal damage may occur. Therefore, careful observation and regular examination of renal function should be carried out. In case of high bun and serum creatinine, the drug should be stopped immediately and appropriate treatment should be taken.
(4) Hepatitis (incidence unknown), liver dysfunction (incidence unknown), jaundice (incidence unknown): due to the significant increase of AST (got), ALT (GPT) and other manifestations of hepatitis and liver dysfunction, attention should be paid to observation. If there is any abnormality, the drug should be stopped immediately and appropriate treatment should be taken.
(5) There may be agranulocytosis (unknown incidence), hemolytic anemia (unknown incidence), thrombocytopenia (unknown incidence). Therefore, attention should be paid to observation. If there is any abnormality, the drug should be stopped immediately and appropriate treatment should be taken.
(6) Pseudomembranous enteritis with hematochezia was rare (less than 0.01%) (initial symptoms: abdominal pain, frequent diarrhea). Therefore, attention should be paid to observation. If there is any abnormality, the drug should be stopped immediately and appropriate treatment should be taken.
(7) There may be interstitial pneumonia with fever, cough, dyspnea, abnormal chest X-ray examination, eosinophilia and other symptoms (the incidence is unknown), pulmonary infiltration with eosinophilia (PIE) syndrome (the incidence is unknown). Once similar symptoms appear, the drug should be stopped immediately and appropriate treatment, such as the use of adrenocortical hormone.
Taboo:
It is forbidden for patients with allergic shock history.
In principle, patients with allergic history of the components contained in this product or cephalosporins are not given drugs, so they should be cautious when they have to use drugs.
Matters needing attention:
1. Use drugs cautiously (the following patients should use drugs cautiously)
(1) Patients with a history of allergy to penicillin antibiotics.
(2) I or my parents and brothers have allergic symptoms such as bronchial asthma, rash and urticaria.
(3) Patients with severe renal damage [blood concentration will rise and half-life will be prolonged] (refer to [notes on usage and dosage] and [pharmacokinetics].
(4) Patients with insufficient oral feeding or non oral maintenance nutrition. Patients with poor general condition (patients who can not supplement vitamin K through food intake will have symptoms of vitamin K deficiency).
(5) The elderly (refer to the item [medication for elderly patients]).
2. Important notes
(1) Because there is no exact method to predict the shock and anaphylactic reaction caused by this product, the following measures should be taken:
1) Medical history should be asked before use, especially allergic history of antibiotics.
2) First aid measures for shock must be prepared when using.
3) From the beginning to the end of administration, patients should keep quiet and observe fully. Especially at the beginning of the administration, full attention should be paid to the observation.
(2) During the administration period, alcohol should be avoided at least one week after administration (refer to [drug interaction]).
3. Impact on clinical test results
(1) In addition to the reaction of r-test and test paper, it is necessary to pay attention to the false positive results of urine sugar test with Benedict's reagent, felling's reagent and clinitest.
(2) When using Jaffer's reaction to check creatinine, the apparent creatinine value may show a high value, which should be paid attention to.
(3) Direct Coombs test, sometimes positive.
4. Other precautions
We hope that during the use of this product, we can regularly check the liver function, renal function, blood and other conditions.
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